Seonwoo Min

Applied Scientist, Amazon

seonwoo.min0 [AT] gmail.com

Bio

I'm an Applied Scientist at Amazon's Stores Foundational AI, starting in January 2025.

At Stores Foundational AI, I work on building Rufus—a new generative AI-powered conversational shopping experience! Before joining Stores Foundational AI, I started at Amazon in October 2023 as part of AWS HealthAI. I worked on building trustworthy NLP solutions for healthcare, including entity linking, document QA, and knowledge graph QA. Previously, during my Ph.D. (2015–2021), my research interest was primarily at the intersection of machine learning and computational biology. I was fortunate to work with talented collaborators on challenging problems, such as CRISPR gene-editing technology and training protein language models.

Before Amazon, I was a Research Scientist at the Fundamental Research Laboratory, LG AI Research, for 1.2 years. I earned my Ph.D. from the Data Science & Artificial Intelligence Laboratory at Seoul National University in 2021. I received my B.S. in Electrical and Computer Engineering from Seoul National University in 2015. I also spent two summers interning at NAVER in 2019 and 2023. I was honored to receive several awards, including the BK21 Plus Outstanding Researcher Award in 2020, the Microsoft Research Asia Fellowship Nomination Award in 2018, and the NRF Global Ph.D. Fellowship (2016–2020).

News

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Publications

Most recent publications on Google Scholar.
indicates equal contribution.

Grounding Visual Representations With Texts for Domain Generalization

Seonwoo Min, Nokyung Park, Siwon Kim, Seunghyun Park, Jinkyu Kim

ECCV 2022: European Conference on Computer Vision

Pre-training of Deep Bidirectional Protein Sequence Representations With Structural Information

Seonwoo Min, Seunghyun Park, Siwon Kim, Hyun-Soo Choi, Sungroh Yoon

IEEE Access 2021 (50+ citations)

Also presented at NeurIPS LMRL Workshop 2019: Neural Information Processing Systems Workshop on Learning Meaningful Representations of Life

Also presented at MLCB Workshop 2019: Workshop on Machine Learrning in Computational Biology (Oral)

Deep Learning Improves Prediction of CRISPR-Cpf1 Guide RNA Activity

Hui Kwon Kim, Seonwoo Min, Myungjae Song, Soobin Jung, Jae Woo Choi, Younggwang Kim, Sangeun Lee, Sungroh Yoon, Hyongbum Kim

Nature Biotechnology 2018 (300+ citations)

Also presented at ISMB Highlights Track 2018: International Conference on Intelligent Systems for Molecular Biology Highlights Track (Oral)

Deep Learning in Bioinformatics

Seonwoo Min, Byunghan Lee, Sungroh Yoon

Briefings in Bioinformatics 2017 (1900+ citations)

Polyphonic Music Generation With Sequence Generative Adversarial Networks

Sang-gil Lee, Uiwon Hwang, Seonwoo Min, Sungroh Yoon

Journal of KIISE 2024

Contrastive Time-Series Anomaly Detection

Hyungi Kim, Siwon Kim, Seonwoo Min, Byunghan Lee

TKDE 2023: IEEE Transactions on Knowledge and Data Engineering

Massively Parallel Evaluation and Computational Prediction of the Activities and Specificities of 17 Small Cas9s

Sang-Yeon Seo, Seonwoo Min, Sungtae Lee, Jung Hwa Seo, Jinman Park, Hui Kwon Kim, Myungjae Song, Dawoon Bae, Sung-Rae Cho, Hyongbum Henry Kim

Nature Methods 2023

Deep Learning Models to Predict the Editing Efficiencies and Outcomes of Diverse Base Editors

Nahye Kim, Sungchul Choi, Sungjae Kim, Myungjae Song, Jung Hwa Seo, Seonwoo Min, Jinman Park, Sung-Rae Cho, Hyongbum Henry Kim

Nature Biotechnology 2023

Sniper2L, a High-Fidelity Cas9 Variant With High Activity

Young-hoon Kim, Nahye Kim, Ikenna Okafor, Sungchul Choi, Seonwoo Min, Joonsun Lee, Keunwoo Choi, Janice Choi, Vinayak Harihar, Youngho Kim, Jin-Soo Kim, Jungjoon K. Lee, Taekjip Ha, Hyongbum Henry Kim

Nature Chemical Biology 2023

Improving Generalization Performance of Electrocardiogram Classification Models

Hyeongrok Han, Seongjae Park, Seonwoo Min, Hyun-Soo Choi, Eunji Kim, Hyunki Kim, Sangha Park, Jinkook Kim, Junsang Park, Junho An, Kwanglo Lee, Wonsun Jeong, Sangil Chon, Kwonwoo Ha, Myungkyu Han, Sungroh Yoon

Physiological Measurement 2023

Pure Transformers Are Powerful Graph Learners

Jinwoo Kim, Dat Tien Nguyen, Seonwoo Min, Sungjun Cho, Moontae Lee, Honglak Lee, Seunghoon Hong

NeurIPS 2022: Neural Information Processing Systems (200+ citations)

Transformers Meet Stochastic Block Models

Sungjun Cho, Seonwoo Min, Jinwoo Kim, Moontae Lee, Honglak Lee, Seunghoon Hong

NeurIPS 2022: Neural Information Processing Systems

Grounding Visual Representations With Texts for Domain Generalization

Seonwoo Min, Nokyung Park, Siwon Kim, Seunghyun Park, Jinkyu Kim

ECCV 2022: European Conference on Computer Vision

TargetNet: Functional microRNA Target Prediction With Deep Neural Networks

Seonwoo Min, Byunghan Lee, Sungroh Yoon

Bioinformatics 2022

DNA Privacy: Analyzing Malicious DNA Sequences Using Deep Neural Networks

Ho Bae, Seonwoo Min, Hyun-Soo Choi, Sungroh Yoon

TCBB 2022: IEEE/ACM Transactions on Computational Biology and Bioinformatics

Supervised Neural Discrete Universal Denoiser for Adaptive Denoising

Sungmin Cha, Seonwoo Min, Sungroh Yoon and Taesup Moon

ArXiv 2021

Generation of a More Efficient Prime Editor 2 by Addition of the Rad51 DNA-Binding Domain

Myungjae Song, Jung Min Lim, Seonwoo Min, Jeong-Seok Oh, Dong Young Kim, Jae-Sung Woo, Hiroshi Nishimasu, Sung-Rae Cho, Sungroh Yoon, Hyongbum Henry Kim

Nature Communications 2021 (50+ citations)

Towards High Generalization Performance on Electrocardiogram Classification

Hyeongrok Han, Seongjae Park, Seonwoo Min, Hyun-Soo Choi, Eunji Kim, Hyunki Kim, Sangha Park, Jinkook Kim, Junsang Park, Junho An, Kwanglo Lee, Wonsun Jeong, Sangil Chon, Kwonwoo Ha, Myungkyu Han, Sungroh Yoon

CinC 2021: Computing in Cardiology (Winner (6, 4-lead) and Runner-up (12, 3, 2-lead) in PhysioNet Challenge)

Pre-training of Deep Bidirectional Protein Sequence Representations With Structural Information

Seonwoo Min, Seunghyun Park, Siwon Kim, Hyun-Soo Choi, Sungroh Yoon

IEEE Access 2021 (50+ citations)

Also presented at NeurIPS LMRL Workshop 2019: Neural Information Processing Systems Workshop on Learning Meaningful Representations of Life

Also presented at MLCB Workshop 2019: Workshop on Machine Learrning in Computational Biology (Oral)

Protein Transfer Learning Improves Identification of Heat Shock Protein Families

Seonwoo Min, Hyungi Kim, Byunghan Lee, Sungroh Yoon

PLOS ONE 2021

Learned Embeddings From Deep Learning to Visualize and Predict Protein Sets

Christian Dallago, Konstantin Schütze, Michael Heinzinger, Tobias Olenyi, Maria Littmann, Amy X. Lu, Kevin K. Yang, Seonwoo Min, Sungroh Yoon, James T. Morton, Burkhard Rost

Current Protocols 2021 (50+ citations)

Also presented at NeurIPS LMRL Workshop 2020: Neural Information Processing Systems Workshop on Learning Meaningful Representations of Life

Also presented at ISMB BioVis Poster Track 2020: International Conference on Intelligent Systems for Molecular Biology BioVis Poster Track

Recording of Elapsed Time and Temporal Information About Biological Events Using Cas9

Jihye Park, Jung Min Lim, Seok-Jae Heo, Jinman Park, Yoojin Chang, Hui Kwon Kim, Dongmin Jung, Ji Hea Yu, Seonwoo Min, Sungroh Yoon, Sung-Rae Cho, Inkyung Jung, Taeyoung Park, Hyongbum Henry Kim

Cell 2021

Predicting the Efficiency of Prime Editing Guide RNAs in Human Cells

Hui Kwon Kim, GooSang Yu, Jinman Park, Seonwoo Min, Sungtae Lee, Sungroh Yoon, Hyongbum Henry Kim

Nature Biotechnology 2020 (200+ citations)

Prediction of the Sequence-Specific Cleavage Activity of Cas9 Variants

Nahye Kim, Hui Kwon Kim, Sungtae Lee, Jung Hwa Seo, Jae Woo Choi, Jinman Park, Seonwoo Min, Sungroh Yoon, Sung-Rae Cho, Hyongbum Henry Kim

Nature Biotechnology 2020 (100+ citations)

Bag of Tricks for Electrocardiogram Classification With Deep Neural Networks

Seonwoo Min, Hyun-Soo Choi, Hyeongrok Han, Minji Seo, Jin-Kook Kim, Junsang Park, Sunghoon Jung, Il-Young Oh, Byunghan Lee, Sungroh Yoon"

CinC 2020: Computing in Cardiology (6th Place in PhysioNet Challenge)

Sequence-Specific Prediction of the Efficiencies of Adenine and Cytosine Base Editors

Myungjae Song, Hui Kwon Kim, Sungtae Lee, Younggwang Kim, Sang-Yeon Seo, Jinman Park, Nahye Kim, Jae Woo Choi, Hyewon Jang, Jeong Hong Shin, Seonwoo Min, Jhejiu Quan, Jihun Kim, Hoon-Chul Kang, Sungroh Yoon, Hyongbum Henry Kim

Nature Biotechnology 2020 (100+ citations)

High-Throughput Analysis of the Activities of xCas9, SpCas9-NG and SpCas9 at Matched and Mismatched Target Sequences in Human Cells

Hui Kwon Kim, Sungtae Lee, Younggwang Kim, Jinman Park, Seonwoo Min, Jae Woo Choi, Tony Huang, Sungroh Yoon, David Liu, Hyongbum Henry Kim

Nature Biomedical Engineering 2020 (100+ citations)

SpCas9 Activity Prediction by DeepSpCas9, a Deep Learning-based Model With High Generalization Performance

Hui Kwon Kim, Younggwang Kim, Sungtae Lee, Seonwoo Min, Jung Yoon Bae, Jae Woo Choi, Jinman Park, Dongmin Jung, Sungroh Yoon, Hyongbum Henry Kim

Science Advances 2019 (200+ citations)

Learning-Based Instantaneous Drowsiness Detection Using Wired and Wireless EEG

Hyun-Soo Choi, Seonwoo Min, Siwon Kim, Ho Bae, Jee-Eun Yoon, Inha Hwang, Dana Oh, Chang-Ho Yun, Sungroh Yoon

IEEE Access 2019

Deep Learning Improves Prediction of CRISPR-Cpf1 Guide RNA Activity

Hui Kwon Kim, Seonwoo Min, Myungjae Song, Soobin Jung, Jae Woo Choi, Younggwang Kim, Sangeun Lee, Sungroh Yoon, Hyongbum Kim

Nature Biotechnology 2018 (300+ citations)

Also presented at ISMB Highlights Track 2018: International Conference on Intelligent Systems for Molecular Biology Highlights Track (Oral)

Deep Learning in Bioinformatics

Seonwoo Min, Byunghan Lee, Sungroh Yoon

Briefings in Bioinformatics 2017 (1900+ citations)

Deep Recurrent Neural Network-Based Identification of Precursor MicroRNAs

Seunghyun Park, Seonwoo Min, Hyun-Soo Choi, Sungroh Yoon

NeurIPS 2017: Neural Information Processing Systems (100+ citations)

Neural Universal Discrete Denoiser

Taesup Moon, Seonwoo Min, Byunghan Lee, Sungroh Yoon

NeurIPS 2016: Neural Information Processing Systems

Polyphonic Music Generation With Sequence Generative Adversarial Networks

Sang-gil Lee, Uiwon Hwang, Seonwoo Min, Sungroh Yoon

Journal of KIISE 2024

Contrastive Time-Series Anomaly Detection

Hyungi Kim, Siwon Kim, Seonwoo Min, Byunghan Lee

TKDE 2023: IEEE Transactions on Knowledge and Data Engineering

Pure Transformers Are Powerful Graph Learners

Jinwoo Kim, Dat Tien Nguyen, Seonwoo Min, Sungjun Cho, Moontae Lee, Honglak Lee, Seunghoon Hong

NeurIPS 2022: Neural Information Processing Systems (200+ citations)

Transformers Meet Stochastic Block Models

Sungjun Cho, Seonwoo Min, Jinwoo Kim, Moontae Lee, Honglak Lee, Seunghoon Hong

NeurIPS 2022: Neural Information Processing Systems

Grounding Visual Representations With Texts for Domain Generalization

Seonwoo Min, Nokyung Park, Siwon Kim, Seunghyun Park, Jinkyu Kim

ECCV 2022: European Conference on Computer Vision

Supervised Neural Discrete Universal Denoiser for Adaptive Denoising

Sungmin Cha, Seonwoo Min, Sungroh Yoon and Taesup Moon

ArXiv 2021

Pre-training of Deep Bidirectional Protein Sequence Representations With Structural Information

Seonwoo Min, Seunghyun Park, Siwon Kim, Hyun-Soo Choi, Sungroh Yoon

IEEE Access 2021 (50+ citations)

Also presented at NeurIPS LMRL Workshop 2019: Neural Information Processing Systems Workshop on Learning Meaningful Representations of Life

Also presented at MLCB Workshop 2019: Workshop on Machine Learrning in Computational Biology (Oral)

Learned Embeddings From Deep Learning to Visualize and Predict Protein Sets

Christian Dallago, Konstantin Schütze, Michael Heinzinger, Tobias Olenyi, Maria Littmann, Amy X. Lu, Kevin K. Yang, Seonwoo Min, Sungroh Yoon, James T. Morton, Burkhard Rost

Current Protocols 2021 (50+ citations)

Also presented at NeurIPS LMRL Workshop 2020: Neural Information Processing Systems Workshop on Learning Meaningful Representations of Life

Also presented at ISMB BioVis Poster Track 2020: International Conference on Intelligent Systems for Molecular Biology BioVis Poster Track

Deep Learning Improves Prediction of CRISPR-Cpf1 Guide RNA Activity

Hui Kwon Kim, Seonwoo Min, Myungjae Song, Soobin Jung, Jae Woo Choi, Younggwang Kim, Sangeun Lee, Sungroh Yoon, Hyongbum Kim

Nature Biotechnology 2018 (300+ citations)

Also presented at ISMB Highlights Track 2018: International Conference on Intelligent Systems for Molecular Biology Highlights Track (Oral)

Deep Recurrent Neural Network-Based Identification of Precursor MicroRNAs

Seunghyun Park, Seonwoo Min, Hyun-Soo Choi, Sungroh Yoon

NeurIPS 2017: Neural Information Processing Systems (100+ citations)

Neural Universal Discrete Denoiser

Taesup Moon, Seonwoo Min, Byunghan Lee, Sungroh Yoon

NeurIPS 2016: Neural Information Processing Systems

Improving Generalization Performance of Electrocardiogram Classification Models

Hyeongrok Han, Seongjae Park, Seonwoo Min, Hyun-Soo Choi, Eunji Kim, Hyunki Kim, Sangha Park, Jinkook Kim, Junsang Park, Junho An, Kwanglo Lee, Wonsun Jeong, Sangil Chon, Kwonwoo Ha, Myungkyu Han, Sungroh Yoon

Physiological Measurement 2023

TargetNet: Functional microRNA Target Prediction With Deep Neural Networks

Seonwoo Min, Byunghan Lee, Sungroh Yoon

Bioinformatics 2022

DNA Privacy: Analyzing Malicious DNA Sequences Using Deep Neural Networks

Ho Bae, Seonwoo Min, Hyun-Soo Choi, Sungroh Yoon

TCBB 2022: IEEE/ACM Transactions on Computational Biology and Bioinformatics

Towards High Generalization Performance on Electrocardiogram Classification

Hyeongrok Han, Seongjae Park, Seonwoo Min, Hyun-Soo Choi, Eunji Kim, Hyunki Kim, Sangha Park, Jinkook Kim, Junsang Park, Junho An, Kwanglo Lee, Wonsun Jeong, Sangil Chon, Kwonwoo Ha, Myungkyu Han, Sungroh Yoon

CinC 2021: Computing in Cardiology (Winner (6, 4-lead) and Runner-up (12, 3, 2-lead) in PhysioNet Challenge)

Pre-training of Deep Bidirectional Protein Sequence Representations With Structural Information

Seonwoo Min, Seunghyun Park, Siwon Kim, Hyun-Soo Choi, Sungroh Yoon

IEEE Access 2021 (50+ citations)

Also presented at NeurIPS LMRL Workshop 2019: Neural Information Processing Systems Workshop on Learning Meaningful Representations of Life

Also presented at MLCB Workshop 2019: Workshop on Machine Learrning in Computational Biology (Oral)

Protein Transfer Learning Improves Identification of Heat Shock Protein Families

Seonwoo Min, Hyungi Kim, Byunghan Lee, Sungroh Yoon

PLOS ONE 2021

Learned Embeddings From Deep Learning to Visualize and Predict Protein Sets

Christian Dallago, Konstantin Schütze, Michael Heinzinger, Tobias Olenyi, Maria Littmann, Amy X. Lu, Kevin K. Yang, Seonwoo Min, Sungroh Yoon, James T. Morton, Burkhard Rost

Current Protocols 2021 (50+ citations)

Also presented at NeurIPS LMRL Workshop 2020: Neural Information Processing Systems Workshop on Learning Meaningful Representations of Life

Also presented at ISMB BioVis Poster Track 2020: International Conference on Intelligent Systems for Molecular Biology BioVis Poster Track

Bag of Tricks for Electrocardiogram Classification With Deep Neural Networks

Seonwoo Min, Hyun-Soo Choi, Hyeongrok Han, Minji Seo, Jin-Kook Kim, Junsang Park, Sunghoon Jung, Il-Young Oh, Byunghan Lee, Sungroh Yoon"

CinC 2020: Computing in Cardiology (6th Place in PhysioNet Challenge)

Learning-Based Instantaneous Drowsiness Detection Using Wired and Wireless EEG

Hyun-Soo Choi, Seonwoo Min, Siwon Kim, Ho Bae, Jee-Eun Yoon, Inha Hwang, Dana Oh, Chang-Ho Yun, Sungroh Yoon

IEEE Access 2019

Deep Learning in Bioinformatics

Seonwoo Min, Byunghan Lee, Sungroh Yoon

Briefings in Bioinformatics 2017 (1900+ citations)

Deep Recurrent Neural Network-Based Identification of Precursor MicroRNAs

Seunghyun Park, Seonwoo Min, Hyun-Soo Choi, Sungroh Yoon

NeurIPS 2017: Neural Information Processing Systems (100+ citations)

Massively Parallel Evaluation and Computational Prediction of the Activities and Specificities of 17 Small Cas9s

Sang-Yeon Seo, Seonwoo Min, Sungtae Lee, Jung Hwa Seo, Jinman Park, Hui Kwon Kim, Myungjae Song, Dawoon Bae, Sung-Rae Cho, Hyongbum Henry Kim

Nature Methods 2023

Deep Learning Models to Predict the Editing Efficiencies and Outcomes of Diverse Base Editors

Nahye Kim, Sungchul Choi, Sungjae Kim, Myungjae Song, Jung Hwa Seo, Seonwoo Min, Jinman Park, Sung-Rae Cho, Hyongbum Henry Kim

Nature Biotechnology 2023

Sniper2L, a High-Fidelity Cas9 Variant With High Activity

Young-hoon Kim, Nahye Kim, Ikenna Okafor, Sungchul Choi, Seonwoo Min, Joonsun Lee, Keunwoo Choi, Janice Choi, Vinayak Harihar, Youngho Kim, Jin-Soo Kim, Jungjoon K. Lee, Taekjip Ha, Hyongbum Henry Kim

Nature Chemical Biology 2023

Generation of a More Efficient Prime Editor 2 by Addition of the Rad51 DNA-Binding Domain

Myungjae Song, Jung Min Lim, Seonwoo Min, Jeong-Seok Oh, Dong Young Kim, Jae-Sung Woo, Hiroshi Nishimasu, Sung-Rae Cho, Sungroh Yoon, Hyongbum Henry Kim

Nature Communications 2021 (50+ citations)

Recording of Elapsed Time and Temporal Information About Biological Events Using Cas9

Jihye Park, Jung Min Lim, Seok-Jae Heo, Jinman Park, Yoojin Chang, Hui Kwon Kim, Dongmin Jung, Ji Hea Yu, Seonwoo Min, Sungroh Yoon, Sung-Rae Cho, Inkyung Jung, Taeyoung Park, Hyongbum Henry Kim

Cell 2021

Predicting the Efficiency of Prime Editing Guide RNAs in Human Cells

Hui Kwon Kim, GooSang Yu, Jinman Park, Seonwoo Min, Sungtae Lee, Sungroh Yoon, Hyongbum Henry Kim

Nature Biotechnology 2020 (200+ citations)

Prediction of the Sequence-Specific Cleavage Activity of Cas9 Variants

Nahye Kim, Hui Kwon Kim, Sungtae Lee, Jung Hwa Seo, Jae Woo Choi, Jinman Park, Seonwoo Min, Sungroh Yoon, Sung-Rae Cho, Hyongbum Henry Kim

Nature Biotechnology 2020 (100+ citations)

Sequence-Specific Prediction of the Efficiencies of Adenine and Cytosine Base Editors

Myungjae Song, Hui Kwon Kim, Sungtae Lee, Younggwang Kim, Sang-Yeon Seo, Jinman Park, Nahye Kim, Jae Woo Choi, Hyewon Jang, Jeong Hong Shin, Seonwoo Min, Jhejiu Quan, Jihun Kim, Hoon-Chul Kang, Sungroh Yoon, Hyongbum Henry Kim

Nature Biotechnology 2020 (100+ citations)

High-Throughput Analysis of the Activities of xCas9, SpCas9-NG and SpCas9 at Matched and Mismatched Target Sequences in Human Cells

Hui Kwon Kim, Sungtae Lee, Younggwang Kim, Jinman Park, Seonwoo Min, Jae Woo Choi, Tony Huang, Sungroh Yoon, David Liu, Hyongbum Henry Kim

Nature Biomedical Engineering 2020 (100+ citations)

SpCas9 Activity Prediction by DeepSpCas9, a Deep Learning-based Model With High Generalization Performance

Hui Kwon Kim, Younggwang Kim, Sungtae Lee, Seonwoo Min, Jung Yoon Bae, Jae Woo Choi, Jinman Park, Dongmin Jung, Sungroh Yoon, Hyongbum Henry Kim

Science Advances 2019 (200+ citations)

Deep Learning Improves Prediction of CRISPR-Cpf1 Guide RNA Activity

Hui Kwon Kim, Seonwoo Min, Myungjae Song, Soobin Jung, Jae Woo Choi, Younggwang Kim, Sangeun Lee, Sungroh Yoon, Hyongbum Kim

Nature Biotechnology 2018 (300+ citations)

Also presented at ISMB Highlights Track 2018: International Conference on Intelligent Systems for Molecular Biology Highlights Track (Oral)

Awards, Honors, and Scholarships

Awards
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Curriculum Vitae

Full CV in PDF.

Acknowledgement

This website uses the template from Prof. Martin Saveski. Thanks for sharing!